VIIa

COMPLEX I 13kDa-A 13kDa-B 15kDa 18kDa 19kDa 20kDa 23kDa 24kDa 30kDa 39kDa 42kDa 49kDa 51kDa 75kDa ACP B8 B12 B14 B14.5a B14.5b B15 B16.6 B17 B17.2 B18 B22 ASHI MLRQ MNLL PDSW SGDH COMPLEX II FP Fe-S CYTb560 CYTb560 small COMPLEX III 6.4kDa 7.2kDa 11kDa 14kDa CYTC1 CP1 CP2 Fe-S UQ-B.QP-C COMPLEX IV IV Va Vb VIa VIb VIc VIIa VIIc COMPLEX V alpha beta gamma delta epsilon b d e f g OSCP Cf6 LBP	Peptide alignment
Identity = 87.6% Similarity = 92.1%
1 Dm MMNLSRAVVRSFATTAGRRSAAVPKDQIEKGYFEIRKVQEHFQKKDGKPVFLKGSVVDNVLYRVTVALALVGIGGMGKLFYELSVPKKE Dp MMNLSRAVVRSFATTTSRRSTAVGKEQIEKGYFEIRKVQEHFQKKDGKPVFLKGSAVDSVLYRVTMALALVGIGGMTKLFYDLSVPKTE
DNA alignment
Colour code: UTRs - Coding - Intron(s) - NRG element(s) - Unknown
1 Dm GATAATACATCGATATATCTCCAGTTGTCAGCTGTCATATTTCAGACCGATATTTTTCGCCCAGGAAAACTG--CTCACTTTTTGCTAAATCTTAAAAAT G CA C A TCTCCA ..CAGCTGTCATA TT C GAT..TTT GCCCAG AAAACT ..CTC C TTT GCTAAA T A AA Dp GGGGTGGCAGCACCAATTCTCCAAAA--CAGCTGTCATAATTTGTCCGGAT--TTTCAGCCCAGAAAAACTTTTCTCGCGTTTAGCTAAAAATATATAAC 101 Dm AAACCC--CAGCAAAATGATGAACCTGTCGAGAGTAAGTAATTTAC----------ATTACTCTACACACCTTTCTGGAGGAACAGCATGAGTTCCGAAA AA C..CAGCAAAATGATGAACCTGTCGAGAGT AGTAA T ..........A TA C ACA C T CTGGA G AGCAT T C G Dp AATATCTTCAGCAAAATGATGAACCTGTCGAGAGTGAGTAAAATTTTGCGACTGGAAATAGCCCACAGGCACTGCTGGATGTGGAGCATTCCTCCAGGGC 201 Dm CACTGGAGATCCCATTACCTACATCCAATTACGTAAGTTCCCTGGAGCCTCA--GAACTAACCGCACATTTTGTACTCCTCGGCAGGCTGTTGTCCGTAG C G A AT TT ...AC CAATTACGTAAG C CTGGAGC CA..GAACTAACCGCACATTTT ....C TC GCAGGC GTTGTCCG AG Dp CTGGGAAAATATAGTTC---ACGGGCAATTACGTAAGGGCGCTGGAGCTCCACCGAACTAACCGCACATTTTC----CGTCTGCAGGCCGTTGTCCGCAG 301 Dm CTTCGCTACCACCGCTGGCCGCCGGTCCGCCGCCGTGCCCAAGGACCAGATCGAGAAGGGATACTTCGAGATCCGCAAGGTGCAGGAGCACTTTCAGAAG CTT GC ACCACC C GCCGCCG TCC CCGC GT CAAGGA CAGATCGAGAAGGGATACTT GAGATCCGCAAGGT CAGGAGCACTT CAGAAG Dp CTTTGCCACCACCACGAGCCGCCGCTCCACCGCTGTCGGCAAGGAACAGATCGAGAAGGGATACTTTGAGATCCGCAAGGTTCAGGAGCACTTCCAGAAG 401 Dm AAGGACGGCAAGCCCGTCTTCCTCAAGGGATCCGTCGTGGACAACGTGCTCTACCGCGTCACCGTCGCTCTCGCCCTCGTCGGCATCGGTGGCATGGGCA AAGGA GGCAAGCCCGTCTTCCTCAAGGG TCCG GT GACA GTGCT TACCGCGTCAC T GC CT GC CT GT GGCAT GGTGGCATG CA Dp AAGGATGGCAAGCCCGTCTTCCTCAAGGGCTCCGCTGTCGACAGTGTGCTGTACCGCGTCACAATGGCACTGGCTCTGGTTGGCATTGGTGGCATGACCA 501 Dm AGCTTTTCTACGAGCTGAGTGTTCCCAAGAAGGAGTGAA---------GTCGCAGTACCGAACCCTAAGCTAAGCCATTAAAC----------------- AGCT TTCTACGA CTGAG GT CCCAAGA GGA T A .........G GC C A C TAAGCTAAGCC TAA C................. Dp AGCTCTTCTACGACCTGAGCGTGCCCAAGACGGAATAATAGAGTGCTTGCAGCGTATTCTACCTTTAAGCTAAGCCTCTAACCAACAGCAAATCCGCAAT 601 Dm -----CCCGCGCAAGATCCGTGATTCAGCGTAGTCGCCTTATATTTCAA-TGTTTTGATTGTGTAAGTTCCATTTTTTAGAATTTTGTGTTTATGCTAGG .....CCCG C A AT GT T CAG GTAGT GCCTTATATTTC .T TTTTGATTGTGT AGT CC T TTT AT G T A ..TA Dp CCAGCCCCGTACCACATTTGTTTTGCAGTGTAGTTGCCTTATATTTCCCCTCTTTTGATTGTGTGAGTGCCTGTATTTGTCATAGCGAAATCAA--TAAT 701 Dm TTGCTAAGTTCTTGACATAAAATATGACATTATC--------CAAGGACAACATTCCGTAAACTATTCCCTGTATTTGTCTAATAAATTTATAGACTATG T AAGT T A T GA T TC........CAAG AA T C C A C T TTTGT T A AA T TA T TG Dp TCAAAAAGTCTTCTTGCAGAGCTGAGAGCTGGTCTACCTGGTCAAGATAAAACTCCTACGCCCCAGAACGTTGCTTTGTGTTAGAATTAACTAAGTTTTG 801 Dm TTTA--AACCTTAAGTTATAATATTTGTTTGCAAACTAGCATCTTAAAGTCTCCGTCTTATACAATAATAGTTTAATTAGGAATTTTATTTGTACAATAA T ..AACC A TT A TTT A T G A TAA C G C TA A A A TTT AT..G A TT AT TG T Dp ATGTGTAACCGAACATTCGCAAGAGCATTTAAAGCGTGGAAATATAAGAGCCTGGCCGTAAAGTAATCAAATTTCAT--GTATCTTAATGTGGCTGCTGC 901 Dm TAGATATGTGTAACATGAGAACCACTTGCCTAAGAGATCTGCCATTCAGATACAACATCTATCCCAAAAGTTTGTAACTAATCGCAATCCTTAATCCCTT T T GT ...CA GA AACCA T CC A CT C AT T CAA A C T.....AAGT A A CGC CTT TC T Dp TGTCTGGGTC---CAGGAAAACCATGTTCCCATTCCCCCTTCTATAATATTGCAATAACATT-----AAGTAAACGAACAGCCGCCGCTCTTTTTCGATG 1001 Dm T---ATCTTGCAGAGCCTTGCCCTGGATACCTGGACAACATGAAACACCCCAACCTACAACCTGGCTTATTGTTTTGTGTTAGAATAGCTAAGATTTGAT ...ATCT AG G CT.GC TGG AC TGG AAC ..................A C GG T T TTT T AA GC A T G Dp GCAGATCTCAGAGGGGCT-GCAGTGGGGACATGGGGAACG------------------ACCAGGGAGTCTGTTTTATAAATCAAAGGGCGGCAACTCGGC 1101 Dm GTGTAAACTGAACATTCGCAAGAGCATTTAAAGCGTGGAAATATAAGAGATCTGGCTGTAA G GT C T G AA TTTAAA CG G AAT ....A T GCT TAA Dp GCGTTGCCATTGGCATGGAAATGCATTTTAAATCGAGCGAATC----ATGTTGCGCTTTAA

COMPLEX I
13kDa-A 13kDa-B
15kDa 18kDa
19kDa 20kDa
23kDa 24kDa
30kDa 39kDa
42kDa 49kDa
51kDa 75kDa
ACP B8 B12
B14 B14.5a
B14.5b B15
B16.6 B17 B17.2
B18 B22 ASHI
MLRQ MNLL
PDSW SGDH

COMPLEX II
FP Fe-S
CYTb560
CYTb560 small

COMPLEX III
6.4kDa 7.2kDa
11kDa 14kDa
CYTC1 CP1 CP2
Fe-S UQ-B.QP-C

COMPLEX IV
IV Va Vb VIa
VIb VIc VIIa VIIc

COMPLEX V
alpha beta
gamma delta
epsilon b d e
f g OSCP
Cf6 LBP

Peptide alignment

Identity = 87.6% Similarity = 92.1%

   1
Dm MMNLSRAVVRSFATTAGRRSAAVPKDQIEKGYFEIRKVQEHFQKKDGKPVFLKGSVVDNVLYRVTVALALVGIGGMGKLFYELSVPKKE
Dp MMNLSRAVVRSFATTTSRRSTAVGKEQIEKGYFEIRKVQEHFQKKDGKPVFLKGSAVDSVLYRVTMALALVGIGGMTKLFYDLSVPKTE

DNA alignment

Colour code: UTRs - Coding - Intron(s) - NRG element(s) - Unknown

   1
Dm GATAATACATCGATATATCTCCAGTTGTCAGCTGTCATATTTCAGACCGATATTTTTCGCCCAGGAAAACTG--CTCACTTTTTGCTAAATCTTAAAAAT
   G      CA C   A  TCTCCA   ..CAGCTGTCATA TT    C GAT..TTT  GCCCAG AAAACT ..CTC C TTT GCTAAA  T  A AA 
Dp GGGGTGGCAGCACCAATTCTCCAAAA--CAGCTGTCATAATTTGTCCGGAT--TTTCAGCCCAGAAAAACTTTTCTCGCGTTTAGCTAAAAATATATAAC
 
   101
Dm AAACCC--CAGCAAAATGATGAACCTGTCGAGAGTAAGTAATTTAC----------ATTACTCTACACACCTTTCTGGAGGAACAGCATGAGTTCCGAAA
   AA   C..CAGCAAAATGATGAACCTGTCGAGAGT AGTAA  T  ..........A TA  C ACA  C  T CTGGA G   AGCAT   T C G   
Dp AATATCTTCAGCAAAATGATGAACCTGTCGAGAGTGAGTAAAATTTTGCGACTGGAAATAGCCCACAGGCACTGCTGGATGTGGAGCATTCCTCCAGGGC
 
   201
Dm CACTGGAGATCCCATTACCTACATCCAATTACGTAAGTTCCCTGGAGCCTCA--GAACTAACCGCACATTTTGTACTCCTCGGCAGGCTGTTGTCCGTAG
   C   G A AT    TT ...AC   CAATTACGTAAG  C CTGGAGC  CA..GAACTAACCGCACATTTT ....C TC GCAGGC GTTGTCCG AG
Dp CTGGGAAAATATAGTTC---ACGGGCAATTACGTAAGGGCGCTGGAGCTCCACCGAACTAACCGCACATTTTC----CGTCTGCAGGCCGTTGTCCGCAG
 
   301
Dm CTTCGCTACCACCGCTGGCCGCCGGTCCGCCGCCGTGCCCAAGGACCAGATCGAGAAGGGATACTTCGAGATCCGCAAGGTGCAGGAGCACTTTCAGAAG
   CTT GC ACCACC C  GCCGCCG TCC CCGC GT   CAAGGA CAGATCGAGAAGGGATACTT GAGATCCGCAAGGT CAGGAGCACTT CAGAAG
Dp CTTTGCCACCACCACGAGCCGCCGCTCCACCGCTGTCGGCAAGGAACAGATCGAGAAGGGATACTTTGAGATCCGCAAGGTTCAGGAGCACTTCCAGAAG
 
   401
Dm AAGGACGGCAAGCCCGTCTTCCTCAAGGGATCCGTCGTGGACAACGTGCTCTACCGCGTCACCGTCGCTCTCGCCCTCGTCGGCATCGGTGGCATGGGCA
   AAGGA GGCAAGCCCGTCTTCCTCAAGGG TCCG  GT GACA  GTGCT TACCGCGTCAC  T GC CT GC CT GT GGCAT GGTGGCATG  CA
Dp AAGGATGGCAAGCCCGTCTTCCTCAAGGGCTCCGCTGTCGACAGTGTGCTGTACCGCGTCACAATGGCACTGGCTCTGGTTGGCATTGGTGGCATGACCA

   501
Dm AGCTTTTCTACGAGCTGAGTGTTCCCAAGAAGGAGTGAA---------GTCGCAGTACCGAACCCTAAGCTAAGCCATTAAAC-----------------
   AGCT TTCTACGA CTGAG GT CCCAAGA GGA T A .........G  GC     C A C  TAAGCTAAGCC  TAA C.................
Dp AGCTCTTCTACGACCTGAGCGTGCCCAAGACGGAATAATAGAGTGCTTGCAGCGTATTCTACCTTTAAGCTAAGCCTCTAACCAACAGCAAATCCGCAAT
 
   601
Dm -----CCCGCGCAAGATCCGTGATTCAGCGTAGTCGCCTTATATTTCAA-TGTTTTGATTGTGTAAGTTCCATTTTTTAGAATTTTGTGTTTATGCTAGG
   .....CCCG  C A AT  GT  T CAG GTAGT GCCTTATATTTC  .T TTTTGATTGTGT AGT CC  T TTT   AT   G   T A ..TA  
Dp CCAGCCCCGTACCACATTTGTTTTGCAGTGTAGTTGCCTTATATTTCCCCTCTTTTGATTGTGTGAGTGCCTGTATTTGTCATAGCGAAATCAA--TAAT
 
   701
Dm TTGCTAAGTTCTTGACATAAAATATGACATTATC--------CAAGGACAACATTCCGTAAACTATTCCCTGTATTTGTCTAATAAATTTATAGACTATG
   T    AAGT  T       A  T  GA  T  TC........CAAG   AA  T C      C A   C T   TTTGT T A AA T   TA   T TG
Dp TCAAAAAGTCTTCTTGCAGAGCTGAGAGCTGGTCTACCTGGTCAAGATAAAACTCCTACGCCCCAGAACGTTGCTTTGTGTTAGAATTAACTAAGTTTTG
 
   801
Dm TTTA--AACCTTAAGTTATAATATTTGTTTGCAAACTAGCATCTTAAAGTCTCCGTCTTATACAATAATAGTTTAATTAGGAATTTTATTTGTACAATAA
    T  ..AACC  A  TT   A      TTT  A   T G A   TAA   C   G C TA A  A    A TTT AT..G A  TT AT TG     T  
Dp ATGTGTAACCGAACATTCGCAAGAGCATTTAAAGCGTGGAAATATAAGAGCCTGGCCGTAAAGTAATCAAATTTCAT--GTATCTTAATGTGGCTGCTGC
 
   901
Dm TAGATATGTGTAACATGAGAACCACTTGCCTAAGAGATCTGCCATTCAGATACAACATCTATCCCAAAAGTTTGTAACTAATCGCAATCCTTAATCCCTT
   T   T  GT ...CA GA AACCA  T CC A      CT C AT     T CAA A C  T.....AAGT     A  A  CGC    CTT  TC  T 
Dp TGTCTGGGTC---CAGGAAAACCATGTTCCCATTCCCCCTTCTATAATATTGCAATAACATT-----AAGTAAACGAACAGCCGCCGCTCTTTTTCGATG
 
   1001
Dm T---ATCTTGCAGAGCCTTGCCCTGGATACCTGGACAACATGAAACACCCCAACCTACAACCTGGCTTATTGTTTTGTGTTAGAATAGCTAAGATTTGAT
    ...ATCT   AG G CT.GC  TGG  AC TGG  AAC ..................A C  GG  T T  TTT     T  AA  GC    A T G  
Dp GCAGATCTCAGAGGGGCT-GCAGTGGGGACATGGGGAACG------------------ACCAGGGAGTCTGTTTTATAAATCAAAGGGCGGCAACTCGGC
 
   1101
Dm GTGTAAACTGAACATTCGCAAGAGCATTTAAAGCGTGGAAATATAAGAGATCTGGCTGTAA
   G GT   C       T G AA     TTTAAA CG G  AAT ....A  T   GCT TAA
Dp GCGTTGCCATTGGCATGGAAATGCATTTTAAATCGAGCGAATC----ATGTTGCGCTTTAA